ENSG00000138311


Homo sapiens

Features
Gene ID: ENSG00000138311
  
Biological name :ZNF365
  
Synonyms : Q70YC4 / Q70YC5 / zinc finger protein 365 / ZNF365
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q21.2
Gene start: 62374192
Gene end: 62672011
  
Corresponding Affymetrix probe sets: 1570121_at (Human Genome U133 Plus 2.0 Array)   206448_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392791
Ensembl peptide - ENSP00000387091
Ensembl peptide - ENSP00000481372
Ensembl peptide - ENSP00000345300
Ensembl peptide - ENSP00000362889
Ensembl peptide - ENSP00000378670
Ensembl peptide - ENSP00000378672
Ensembl peptide - ENSP00000378674
Ensembl peptide - ENSP00000378675
NCBI entrez gene - 22891     See in Manteia.
OMIM - 607818
RefSeq - XM_017015941
RefSeq - NM_014951
RefSeq - NM_199450
RefSeq - NM_199451
RefSeq - NM_199452
RefSeq - XM_017015938
RefSeq - XM_017015940
RefSeq Peptide - NP_955523
RefSeq Peptide - NP_955524
RefSeq Peptide - NP_055766
RefSeq Peptide - NP_955522
swissprot - Q70YC4
swissprot - Q70YC5
swissprot - C9J1G1
swissprot - Q08ER3
swissprot - Q495P1
Ensembl - ENSG00000138311
  
Related genetic diseases (OMIM): 605990 - {Nephrolithiasis, uric acid, susceptibility to}, 605990
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf365ENSDARG00000087985Danio rerio
 ZNF365ENSGALG00000002967Gallus gallus
 Q8BG89ENSMUSG00000037855Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBXO41 / Q8TF61 / F-box protein 41ENSG0000016301326


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IMP
 biological_processGO:0000723 telomere maintenance IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IMP
 biological_processGO:0010977 negative regulation of neuron projection development IDA
 biological_processGO:0021687 cerebellar molecular layer morphogenesis IEA
 biological_processGO:0033566 gamma-tubulin complex localization IMP
 biological_processGO:0048714 positive regulation of oligodendrocyte differentiation IEA
 biological_processGO:0060997 dendritic spine morphogenesis IEA
 biological_processGO:0110026 regulation of DNA strand resection involved in replication fork processing IMP
 biological_processGO:0140059 dendrite arborization IEA
 cellular_componentGO:0000930 gamma-tubulin complex IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000504 Abnormality of vision "Abnormality of eyesight (visual perception)." [HPO:curators]
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 HP:0000738 Hallucinations 
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 HP:0001262 Somnolence 
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 HP:0001279 Syncope "Syncope refers to a generalized weakness of muscles with loss of postural tone, inability to stand upright, and loss of consciousness. Once the patient is in a horizontal position, blood flow to the brain is no longer hindered by gravitation and consciousness is regained. Unconsciousness usually lasts for seconds to minutes. Headache and drowsiness (which usually follow seizures) do not follow a syncopal attack. Syncope results from a sudden impairment of brain metabolism usually due to a reduction in cerebral blood flow. This term refers to an abnormally increased disposition to syncope." [HPO:curators]
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 HP:0001350 Slurred speech 
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 HP:0001513 Obesity "A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY)." [MeSH:D009765]
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 HP:0002189 Excessive daytime sleepiness 
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 HP:0002494 Abnormal rapid eye movement (REM) sleep "Abnormality of REM sleep. Phases of REM sleep are characterized by desynchronized EEG patterns, increases in heart rate and blood pressure, sympathetic activation, and a profound loss of muscle tonus except for the eye and middle-ear muscles. There are then phases of rapid eye movements." [HPO:curators]
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 HP:0002524 Cataplexy 
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 HP:0010534 Transient global amnesia "A paroxysmal, transient loss of memory function with preservation of immediate recall and remote memory but with a severe impairment of memory for recent events and ability to retain new information." [HPO:curators]
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 HP:0100785 Insomnia 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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