ENSG00000138617


Homo sapiens

Features
Gene ID: ENSG00000138617
  
Biological name :PARP16
  
Synonyms : PARP16 / poly(ADP-ribose) polymerase family member 16 / Q8N5Y8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q22.31
Gene start: 65234460
Gene end: 65300618
  
Corresponding Affymetrix probe sets: 219034_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457982
Ensembl peptide - ENSP00000261888
Ensembl peptide - ENSP00000396118
NCBI entrez gene - 54956     See in Manteia.
RefSeq - XM_017022389
RefSeq - XM_006720590
RefSeq - XM_006720592
RefSeq - XM_011521742
RefSeq - XM_017022386
RefSeq - XM_017022387
RefSeq - XM_017022388
RefSeq - NM_001316943
RefSeq - NM_001316944
RefSeq - NM_017851
RefSeq - XM_006720589
RefSeq Peptide - NP_060321
RefSeq Peptide - NP_001303872
RefSeq Peptide - NP_001303873
swissprot - H3BV75
swissprot - Q8N5Y8
swissprot - A0A024R5Y7
Ensembl - ENSG00000138617
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp16ENSDARG00000018593Danio rerio
 PARP16ENSGALG00000007365Gallus gallus
 Parp16ENSMUSG00000032392Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006471 protein ADP-ribosylation IMP
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0006987 obsolete activation of signaling protein activity involved in unfolded protein response IMP
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IMP
 biological_processGO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway TAS
 biological_processGO:0060548 negative regulation of cell death IMP
 biological_processGO:0070213 protein auto-ADP-ribosylation IMP
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IMP
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005783 endoplasmic reticulum IMP
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0071782 endoplasmic reticulum tubular network IMP
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity IMP


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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