ENSG00000140526


Homo sapiens

Features
Gene ID: ENSG00000140526
  
Biological name :ABHD2
  
Synonyms : ABHD2 / abhydrolase domain containing 2 / P08910
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q26.1
Gene start: 89087459
Gene end: 89202360
  
Corresponding Affymetrix probe sets: 205566_at (Human Genome U133 Plus 2.0 Array)   221815_at (Human Genome U133 Plus 2.0 Array)   225337_at (Human Genome U133 Plus 2.0 Array)   228490_at (Human Genome U133 Plus 2.0 Array)   63825_at (Human Genome U133 Plus 2.0 Array)   87100_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000268129
Ensembl peptide - ENSP00000454645
Ensembl peptide - ENSP00000455639
Ensembl peptide - ENSP00000457882
Ensembl peptide - ENSP00000454531
NCBI entrez gene - 11057     See in Manteia.
OMIM - 612196
RefSeq - XM_011521165
RefSeq - NM_007011
RefSeq - NM_152924
RefSeq - XM_005254832
RefSeq - XM_005254833
RefSeq Peptide - NP_008942
RefSeq Peptide - NP_690888
swissprot - H3BN19
swissprot - H3BUZ6
swissprot - P08910
swissprot - H3BMT2
swissprot - A0A024RC89
Ensembl - ENSG00000140526
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abhd2aENSDARG00000025797Danio rerio
 abhd2bENSDARG00000045804Danio rerio
 ABHD2ENSGALG00000006689Gallus gallus
 Abhd2ENSMUSG00000039202Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABHD3 / Q8WU67 / abhydrolase domain containing 3ENSG0000015820121
ABHD1 / Q96SE0 / abhydrolase domain containing 1ENSG0000014399420
ABHD15 / Q6UXT9 / abhydrolase domain containing 15ENSG0000016879218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR000952  AB hydrolase 4, conserved site
 IPR012020  AB hydrolase 4 family
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007340 acrosome reaction IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0032570 response to progesterone IDA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IDA
 biological_processGO:0046464 acylglycerol catabolic process IDA
 biological_processGO:0048240 sperm capacitation IDA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0036126 sperm flagellum IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097524 sperm plasma membrane IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042562 hormone binding IDA
 molecular_functionGO:0047372 acylglycerol lipase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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