ENSG00000140543


Homo sapiens

Features
Gene ID: ENSG00000140543
  
Biological name :DET1
  
Synonyms : DET1 / DET1, COP1 ubiquitin ligase partner / Q7L5Y6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q26.1
Gene start: 88494440
Gene end: 88546675
  
Corresponding Affymetrix probe sets: 1558348_at (Human Genome U133 Plus 2.0 Array)   219641_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453900
Ensembl peptide - ENSP00000452856
Ensembl peptide - ENSP00000456340
Ensembl peptide - ENSP00000268148
Ensembl peptide - ENSP00000408994
Ensembl peptide - ENSP00000452613
NCBI entrez gene - 55070     See in Manteia.
OMIM - 608727
RefSeq - NM_001144074
RefSeq - NM_001321596
RefSeq - NM_017996
RefSeq - NM_001321594
RefSeq Peptide - NP_001137546
RefSeq Peptide - NP_001308525
RefSeq Peptide - NP_060466
RefSeq Peptide - NP_001308523
swissprot - Q7L5Y6
swissprot - A0A024RC56
swissprot - H0YK09
swissprot - H0YN79
Ensembl - ENSG00000140543
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 det1ENSDARG00000098247Danio rerio
 DET1ENSGALG00000006750Gallus gallus
 Det1ENSMUSG00000030610Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019138  De-etiolated protein 1, Det1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IPI
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IPI
 biological_processGO:0065003 protein-containing complex assembly IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0031464 Cul4A-RING E3 ubiquitin ligase complex IDA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IMP
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination IPI


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr