ENSG00000140995


Homo sapiens

Features
Gene ID: ENSG00000140995
  
Biological name :DEF8
  
Synonyms : DEF8 / differentially expressed in FDCP 8 homolog / Q6ZN54
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q24.3
Gene start: 89947925
Gene end: 89968060
  
Corresponding Affymetrix probe sets: 219646_at (Human Genome U133 Plus 2.0 Array)   225637_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482524
Ensembl peptide - ENSP00000268676
Ensembl peptide - ENSP00000412784
Ensembl peptide - ENSP00000454478
Ensembl peptide - ENSP00000454534
Ensembl peptide - ENSP00000454930
Ensembl peptide - ENSP00000455654
Ensembl peptide - ENSP00000455783
Ensembl peptide - ENSP00000455987
Ensembl peptide - ENSP00000456095
Ensembl peptide - ENSP00000456157
Ensembl peptide - ENSP00000456501
Ensembl peptide - ENSP00000456706
Ensembl peptide - ENSP00000456799
Ensembl peptide - ENSP00000456954
Ensembl peptide - ENSP00000457072
Ensembl peptide - ENSP00000457309
Ensembl peptide - ENSP00000457627
Ensembl peptide - ENSP00000458019
Ensembl peptide - ENSP00000480073
NCBI entrez gene - 54849     See in Manteia.
RefSeq - XM_017023369
RefSeq - NM_017702
RefSeq - NM_207514
RefSeq - XM_005256318
RefSeq - XM_011523156
RefSeq - XM_011523157
RefSeq - XM_011523158
RefSeq - XM_011523159
RefSeq - XM_011523160
RefSeq - XM_011523161
RefSeq - XM_011523162
RefSeq - XM_017023358
RefSeq - XM_017023359
RefSeq - XM_017023360
RefSeq - XM_017023361
RefSeq - XM_017023362
RefSeq - XM_017023363
RefSeq - XM_017023364
RefSeq - XM_017023365
RefSeq - XM_017023366
RefSeq - XM_017023367
RefSeq - XM_017023368
RefSeq - NM_001242816
RefSeq - NM_001242817
RefSeq - NM_001242818
RefSeq - NM_001242819
RefSeq - NM_001242820
RefSeq - NM_001242821
RefSeq - NM_001242822
RefSeq Peptide - NP_001229746
RefSeq Peptide - NP_001229747
RefSeq Peptide - NP_001229748
RefSeq Peptide - NP_001229749
RefSeq Peptide - NP_001229750
RefSeq Peptide - NP_001229751
RefSeq Peptide - NP_060172
RefSeq Peptide - NP_997397
RefSeq Peptide - NP_001229745
swissprot - H3BTS7
swissprot - H3BMT5
swissprot - Q6ZN54
swissprot - H3BMP4
swissprot - H3BNN0
swissprot - H3BQ81
swissprot - H3BQH5
swissprot - H3BQX9
swissprot - H3BRA7
swissprot - H3BSH6
swissprot - H3BT01
swissprot - H3BT87
Ensembl - ENSG00000140995
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 def8ENSDARG00000068208Danio rerio
 DEF8ENSGALG00000025712Gallus gallus
 Def8ENSMUSG00000001482Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y4G2 / PLEKHM1 / pleckstrin homology and RUN domain containing M1ENSG0000022519027
Q6ZWE6 / PLEKHM3 / pleckstrin homology domain containing M3ENSG0000017838522
RUBCN / Q92622 / RUN and cysteine rich domain containing beclin 1 interacting proteinENSG0000014501621
Q9H714 / RUBCNL / RUN and cysteine rich domain containing beclin 1 interacting protein likeENSG0000010244517


Protein motifs (from Interpro)
Interpro ID Name
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR025258  Putative zinc-RING and/or ribbon
 IPR036280  Multiheme cytochrome superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032418 lysosome localization ISS
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0045780 positive regulation of bone resorption ISS
 biological_processGO:1900029 positive regulation of ruffle assembly ISS
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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