ENSG00000143125


Homo sapiens

Features
Gene ID: ENSG00000143125
  
Biological name :PROK1
  
Synonyms : P58294 / PROK1 / prokineticin 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.3
Gene start: 110451200
Gene end: 110457354
  
Corresponding Affymetrix probe sets: 229124_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000271331
NCBI entrez gene - 84432     See in Manteia.
OMIM - 606233
RefSeq - NM_032414
RefSeq Peptide - NP_115790
swissprot - A0A024R0B1
swissprot - P58294
Ensembl - ENSG00000143125
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prok1ENSDARG00000073948Danio rerio
 PROK1ENSGALG00000040082Gallus gallus
 Prok1ENSMUSG00000070368Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PROK2 / Q9HC23 / prokineticin 2ENSG0000016342146


Protein motifs (from Interpro)
Interpro ID Name
 IPR009523  Prokineticin
 IPR023569  Prokineticin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IBA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007623 circadian rhythm IBA
 biological_processGO:0008284 positive regulation of cell proliferation IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0045765 regulation of angiogenesis IBA
 biological_processGO:0051781 positive regulation of cell division IEA
 cellular_componentGO:0005576 extracellular region IBA
 molecular_functionGO:0001664 G-protein coupled receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000169618 PROKR1 / Q8TCW9 / prokineticin receptor 1  / complex / reaction
 ENSG00000101292 PROKR2 / Q8NFJ6 / prokineticin receptor 2  / complex / reaction






 

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