ENSG00000143294


Homo sapiens

Features
Gene ID: ENSG00000143294
  
Biological name :PRCC
  
Synonyms : papillary renal cell carcinoma (translocation-associated) / PRCC / Q92733
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.1
Gene start: 156750610
Gene end: 156800817
  
Corresponding Affymetrix probe sets: 208938_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434762
Ensembl peptide - ENSP00000271526
Ensembl peptide - ENSP00000403560
NCBI entrez gene - 5546     See in Manteia.
OMIM - 179755
RefSeq - XM_005245314
RefSeq - NM_005973
RefSeq - XM_005245313
RefSeq Peptide - NP_005964
swissprot - A0A0S2Z456
swissprot - Q92733
swissprot - H0Y679
swissprot - H0YE12
Ensembl - ENSG00000143294
  
Related genetic diseases (OMIM): 605074 - Renal cell carcinoma, papillary, 605074
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prccENSDARG00000063252Danio rerio
 PRCCENSGALG00000040696Gallus gallus
 PrccENSMUSG00000004895Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018800  Proline-rich protein PRCC


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007093 mitotic cell cycle checkpoint IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000006 Autosomal dominant inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele." [HPO:curators]
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 HP:0003829 Incomplete penetrance 
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 HP:0006766 Papillary renal cell carcinoma 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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