ENSG00000144401


Homo sapiens

Features
Gene ID: ENSG00000144401
  
Biological name :METTL21A
  
Synonyms : methyltransferase like 21A / METTL21A / Q8WXB1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q33.3
Gene start: 207580631
Gene end: 207625928
  
Corresponding Affymetrix probe sets: 1553743_at (Human Genome U133 Plus 2.0 Array)   235177_at (Human Genome U133 Plus 2.0 Array)   235931_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000409485
Ensembl peptide - ENSP00000407622
Ensembl peptide - ENSP00000415115
Ensembl peptide - ENSP00000416570
Ensembl peptide - ENSP00000272839
Ensembl peptide - ENSP00000385481
Ensembl peptide - ENSP00000389684
Ensembl peptide - ENSP00000392062
Ensembl peptide - ENSP00000400730
Ensembl peptide - ENSP00000403317
NCBI entrez gene - 151194     See in Manteia.
OMIM - 615257
RefSeq - XM_017003450
RefSeq - XM_005246339
RefSeq - XM_005246340
RefSeq - XM_005246341
RefSeq - XM_006712327
RefSeq - XM_006712329
RefSeq - XM_011510724
RefSeq - XM_011510725
RefSeq - XM_011510727
RefSeq - XM_011510728
RefSeq - XM_017003442
RefSeq - XM_017003443
RefSeq - XM_017003445
RefSeq - XM_017003446
RefSeq - XM_017003448
RefSeq - XM_017003449
RefSeq - NM_001127395
RefSeq - NM_001308021
RefSeq - NM_001330130
RefSeq - NM_145280
RefSeq - XM_005246336
RefSeq - XM_005246337
RefSeq - XM_005246338
RefSeq Peptide - NP_001317065
RefSeq Peptide - NP_001317061
RefSeq Peptide - NP_001317062
RefSeq Peptide - NP_001317063
RefSeq Peptide - NP_001317064
RefSeq Peptide - NP_001317066
RefSeq Peptide - NP_660323
RefSeq Peptide - NP_001120867
RefSeq Peptide - NP_001294950
RefSeq Peptide - NP_001317059
RefSeq Peptide - NP_001317060
swissprot - H7BXH9
swissprot - C9JES0
swissprot - C9JSX1
swissprot - Q8WXB1
Ensembl - ENSG00000144401
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5BLD8ENSDARG00000012051Danio rerio
 METTL21AENSGALG00000008493Gallus gallus
 Q9CQL0ENSMUSG00000025956Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96AZ1 / EEF1AKMT3 / EEF1A lysine methyltransferase 3ENSG0000012342739
Q9H867 / VCPKMT / valosin containing protein lysine methyltransferaseENSG0000010048329
Q5VZV1 / METTL21C / methyltransferase like 21CENSG0000013978028


Protein motifs (from Interpro)
Interpro ID Name
 IPR019410  Lysine methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006479 protein methylation TAS
 biological_processGO:0018022 peptidyl-lysine methylation IDA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008276 protein methyltransferase activity IDA
 molecular_functionGO:0016279 protein-lysine N-methyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030544 Hsp70 protein binding IPI
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
Protein methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109971 HSPA8 / P11142 / heat shock protein family A (Hsp70) member 8  / reaction






 

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