ENSG00000145907


Homo sapiens

Features
Gene ID: ENSG00000145907
  
Biological name :G3BP1
  
Synonyms : G3BP1 / G3BP stress granule assembly factor 1 / Q13283
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q33.1
Gene start: 151771045
Gene end: 151812785
  
Corresponding Affymetrix probe sets: 1557350_at (Human Genome U133 Plus 2.0 Array)   201503_at (Human Genome U133 Plus 2.0 Array)   201514_s_at (Human Genome U133 Plus 2.0 Array)   222187_x_at (Human Genome U133 Plus 2.0 Array)   225007_at (Human Genome U133 Plus 2.0 Array)   242422_at (Human Genome U133 Plus 2.0 Array)   244396_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428926
Ensembl peptide - ENSP00000486887
Ensembl peptide - ENSP00000430738
Ensembl peptide - ENSP00000430480
Ensembl peptide - ENSP00000430045
Ensembl peptide - ENSP00000429920
Ensembl peptide - ENSP00000429316
Ensembl peptide - ENSP00000429250
Ensembl peptide - ENSP00000348578
Ensembl peptide - ENSP00000377681
Ensembl peptide - ENSP00000427810
Ensembl peptide - ENSP00000428469
NCBI entrez gene - 10146     See in Manteia.
OMIM - 608431
RefSeq - XM_017008923
RefSeq - NM_005754
RefSeq - NM_198395
RefSeq - XM_006714749
RefSeq - XM_006714750
RefSeq - XM_017008922
RefSeq Peptide - NP_005745
RefSeq Peptide - NP_938405
swissprot - Q13283
swissprot - E5RIF8
swissprot - E5RI46
swissprot - E5RH42
swissprot - E5RH00
swissprot - Q5U0Q1
swissprot - E5RIZ6
swissprot - E5RJU8
Ensembl - ENSG00000145907
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 g3bp1ENSDARG00000017741Danio rerio
 G3BP1ENSGALG00000004160Gallus gallus
 G3bp1ENSMUSG00000018583Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
G3BP2 / Q9UN86 / G3BP stress granule assembly factor 2ENSG0000013875767


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002075  Nuclear transport factor 2
 IPR018222  Nuclear transport factor 2, eukaryote
 IPR032710  NTF2-like domain superfamily
 IPR034374  G3BP1, RNA recognition motif
 IPR034375  Ras GTPase-activating protein-bianding protein 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007265 Ras protein signal transduction TAS
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0010494 cytoplasmic stress granule IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity TAS
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity TAS
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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