ENSG00000145920


Homo sapiens

Features
Gene ID: ENSG00000145920
  
Biological name :CPLX2
  
Synonyms : complexin 2 / CPLX2 / Q6PUV4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q35.2
Gene start: 175796310
Gene end: 175884020
  
Corresponding Affymetrix probe sets: 206368_at (Human Genome U133 Plus 2.0 Array)   225815_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421106
Ensembl peptide - ENSP00000425973
Ensembl peptide - ENSP00000425284
Ensembl peptide - ENSP00000424305
Ensembl peptide - ENSP00000423612
Ensembl peptide - ENSP00000423564
Ensembl peptide - ENSP00000421825
Ensembl peptide - ENSP00000352544
Ensembl peptide - ENSP00000377346
NCBI entrez gene - 10814     See in Manteia.
OMIM - 605033
RefSeq - XM_017008964
RefSeq - NM_001008220
RefSeq - NM_006650
RefSeq - XM_005265798
RefSeq - XM_005265799
RefSeq - XM_011534419
RefSeq Peptide - NP_006641
RefSeq Peptide - NP_001008221
swissprot - D6RBA5
swissprot - D6R960
swissprot - D6RGY3
swissprot - D6RI05
swissprot - Q6PUV4
swissprot - D6RDN3
Ensembl - ENSG00000145920
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cplx2ENSDARG00000061918Danio rerio
 ENSGALG00000027920Gallus gallus
 Cplx2ENSMUSG00000025867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPLX1 / O14810 / complexin 1ENSG0000016899384


Protein motifs (from Interpro)
Interpro ID Name
 IPR008849  Synaphin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006904 vesicle docking involved in exocytosis TAS
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0016079 synaptic vesicle exocytosis IEA
 biological_processGO:0017157 regulation of exocytosis TAS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031915 positive regulation of synaptic plasticity ISS
 biological_processGO:0043303 mast cell degranulation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031201 SNARE complex IEA
 cellular_componentGO:0042629 mast cell granule IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex IEA
 cellular_componentGO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex TAS
 molecular_functionGO:0000149 SNARE binding IEA
 molecular_functionGO:0017075 syntaxin-1 binding IEA
 molecular_functionGO:0019905 syntaxin binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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