ENSG00000146425


Homo sapiens

Features
Gene ID: ENSG00000146425
  
Biological name :DYNLT1
  
Synonyms : dynein light chain Tctex-type 1 / DYNLT1 / P63172
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q25.3
Gene start: 158636474
Gene end: 158644739
  
Corresponding Affymetrix probe sets: 201999_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356056
NCBI entrez gene - 6993     See in Manteia.
OMIM - 601554
RefSeq - NM_006519
RefSeq - NM_001291602
RefSeq - NM_001291603
RefSeq Peptide - NP_001278531
RefSeq Peptide - NP_001278532
RefSeq Peptide - NP_006510
swissprot - P63172
Ensembl - ENSG00000146425
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dynlt1ENSDARG00000045909Danio rerio
 DYNLT1ENSGALG00000019979Gallus gallus
 Dynlt1ENSMUSG00000096255Mus musculus
 P51807ENSMUSG00000095677Mus musculus
 P51807ENSMUSG00000000579Mus musculus
 P51807ENSMUSG00000092074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DYNLT3 / P51808 / dynein light chain Tctex-type 3ENSG0000016516954


Protein motifs (from Interpro)
Interpro ID Name
 IPR005334  Tctex-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000132 establishment of mitotic spindle orientation ISS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway ISS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019060 intracellular transport of viral protein in host cell IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050768 negative regulation of neurogenesis ISS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus IEA
 biological_processGO:0075606 transport of viral material towards nucleus IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005868 cytoplasmic dynein complex IDA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0043657 host cell IEA
 cellular_componentGO:0099503 secretory vesicle IDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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