ENSG00000148346


Homo sapiens

Features
Gene ID: ENSG00000148346
  
Biological name :LCN2
  
Synonyms : LCN2 / lipocalin 2 / P80188
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 128149071
Gene end: 128153455
  
Corresponding Affymetrix probe sets: 212531_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362089
Ensembl peptide - ENSP00000362108
Ensembl peptide - ENSP00000277480
NCBI entrez gene - 3934     See in Manteia.
OMIM - 600181
RefSeq - NM_005564
RefSeq Peptide - NP_005555
swissprot - P80188
swissprot - X6R8F3
Ensembl - ENSG00000148346
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LCN12 / Q6JVE5 / lipocalin 12ENSG0000018492532


Protein motifs (from Interpro)
Interpro ID Name
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR002345  Lipocalin
 IPR003087  Neutrophil gelatinase-associated lipocalin/epididymal-specific lipocalin-12
 IPR012674  Calycin
 IPR022272  Lipocalin family conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0015891 siderophore transport ISS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045087 innate immune response ISS
 biological_processGO:0055072 iron ion homeostasis IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005506 iron ion binding ISS
 molecular_functionGO:0036094 small molecule binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000092096 Q8WUG5 / SLC22A17 / solute carrier family 22 member 17  / reaction / complex






 

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