ENSG00000149089


Homo sapiens

Features
Gene ID: ENSG00000149089
  
Biological name :APIP
  
Synonyms : APAF1 interacting protein / APIP / Q96GX9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p13
Gene start: 34853094
Gene end: 34916499
  
Corresponding Affymetrix probe sets: 218698_at (Human Genome U133 Plus 2.0 Array)   232630_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379133
Ensembl peptide - ENSP00000474191
NCBI entrez gene - 51074     See in Manteia.
OMIM - 612491
RefSeq - XM_017017875
RefSeq - NM_015957
RefSeq - XM_011520154
RefSeq Peptide - NP_057041
swissprot - S4R3D6
swissprot - Q96GX9
Ensembl - ENSG00000149089
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apipENSDARG00000003132Danio rerio
 APIPENSGALG00000031286Gallus gallus
 ApipENSMUSG00000010911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001303  Class II aldolase/adducin N-terminal
 IPR017714  Methylthioribulose-1-phosphate dehydratase
 IPR027514  Methylthioribulose-1-phosphate dehydratase, eukaryotes
 IPR036409  Class II aldolase/adducin N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process IEA
 biological_processGO:0009086 methionine biosynthetic process IEA
 biological_processGO:0019509 L-methionine salvage from methylthioadenosine IMP
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0051289 protein homotetramerization IDA
 biological_processGO:0070269 pyroptosis IMP
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046570 methylthioribulose 1-phosphate dehydratase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Methionine salvage pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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