ENSG00000149115


Homo sapiens

Features
Gene ID: ENSG00000149115
  
Biological name :TNKS1BP1
  
Synonyms : Q9C0C2 / tankyrase 1 binding protein 1 / TNKS1BP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.1
Gene start: 57299638
Gene end: 57324952
  
Corresponding Affymetrix probe sets: 224792_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431616
Ensembl peptide - ENSP00000494351
Ensembl peptide - ENSP00000437271
Ensembl peptide - ENSP00000433576
Ensembl peptide - ENSP00000350990
NCBI entrez gene - 85456     See in Manteia.
OMIM - 607104
RefSeq - NM_033396
RefSeq - XM_011545325
RefSeq - XM_006718725
RefSeq Peptide - NP_203754
swissprot - E9PKK0
swissprot - Q9C0C2
swissprot - A0A024R542
swissprot - E9PKE7
Ensembl - ENSG00000149115
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-138n13.1ENSDARG00000075349Danio rerio
 P58871ENSMUSG00000033955Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BY89 / KIAA1671ENSG0000019707713


Protein motifs (from Interpro)
Interpro ID Name
 IPR032764  Tankyrase 1-binding protein, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening TAS
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007004 telomere maintenance via telomerase NAS
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IMP
 biological_processGO:0031954 positive regulation of protein autophosphorylation IMP
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0071479 cellular response to ionizing radiation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005720 nuclear heterochromatin IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0030014 CCR4-NOT complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IDA
 molecular_functionGO:0044877 protein-containing complex binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0071532 ankyrin repeat binding IMP


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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