ENSG00000150459


Homo sapiens

Features
Gene ID: ENSG00000150459
  
Biological name :SAP18
  
Synonyms : O00422 / SAP18 / Sin3A associated protein 18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q12.11
Gene start: 21140514
Gene end: 21149084
  
Corresponding Affymetrix probe sets: 208740_at (Human Genome U133 Plus 2.0 Array)   208741_at (Human Genome U133 Plus 2.0 Array)   208742_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475925
Ensembl peptide - ENSP00000481842
Ensembl peptide - ENSP00000371973
Ensembl peptide - ENSP00000391846
Ensembl peptide - ENSP00000475358
Ensembl peptide - ENSP00000475435
NCBI entrez gene - 10284     See in Manteia.
OMIM - 602949
RefSeq - NM_005870
RefSeq Peptide - NP_005861
swissprot - U3KPY7
swissprot - U3KQ12
swissprot - X6RAL5
swissprot - H7BZW6
swissprot - O00422
Ensembl - ENSG00000150459
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sap18ENSDARG00000057854Danio rerio
 SAP18ENSGALG00000017129Gallus gallus
 Sap18ENSMUSG00000021963Mus musculus
 Sap18bENSMUSG00000061104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010516  Sin3 associated polypeptide p18
 IPR017250  Histone deacetylase complex, SAP18 subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IDA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000118 histone deacetylase complex TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0035145 exon-exon junction complex IDA
 cellular_componentGO:0061574 ASAP complex IDA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004407 histone deacetylase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
NoRC negatively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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