ENSG00000154059


Homo sapiens

Features
Gene ID: ENSG00000154059
  
Biological name :IMPACT
  
Synonyms : IMPACT / impact RWD domain protein / Q9P2X3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q11.2
Gene start: 24426616
Gene end: 24453535
  
Corresponding Affymetrix probe sets: 218637_at (Human Genome U133 Plus 2.0 Array)   222698_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000462769
Ensembl peptide - ENSP00000463895
Ensembl peptide - ENSP00000464363
Ensembl peptide - ENSP00000284202
Ensembl peptide - ENSP00000463710
NCBI entrez gene - 55364     See in Manteia.
OMIM - 615319
RefSeq - XM_017025832
RefSeq - NM_018439
RefSeq Peptide - NP_060909
swissprot - J3QQU0
swissprot - J3QRS6
swissprot - J3KT25
swissprot - Q9P2X3
swissprot - J3QLU6
Ensembl - ENSG00000154059
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 impactENSDARG00000043288Danio rerio
 IMPACTENSGALG00000015093Gallus gallus
 ImpactENSMUSG00000024423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001498  Impact, N-terminal
 IPR006575  RWD domain
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR020569  Uncharacterised protein family UPF0029, Impact, conserved site
 IPR023582  Impact family
 IPR036956  Impact, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006446 regulation of translational initiation IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031333 negative regulation of protein complex assembly IEA
 biological_processGO:0031953 negative regulation of protein autophosphorylation IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0042149 cellular response to glucose starvation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0071264 positive regulation of translational initiation in response to starvation IEA
 biological_processGO:0071468 cellular response to acidic pH IEA
 biological_processGO:0071494 cellular response to UV-C IEA
 biological_processGO:0072755 cellular response to benomyl IEA
 biological_processGO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress IEA
 biological_processGO:1990138 neuron projection extension IEA
 biological_processGO:1990253 cellular response to leucine starvation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005844 polysome IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0043022 ribosome binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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