ENSG00000154839


Homo sapiens

Features
Gene ID: ENSG00000154839
  
Biological name :SKA1
  
Synonyms : Q96BD8 / SKA1 / spindle and kinetochore associated complex subunit 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.1
Gene start: 50374995
Gene end: 50394173
  
Corresponding Affymetrix probe sets: 217640_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397222
Ensembl peptide - ENSP00000467559
Ensembl peptide - ENSP00000467242
Ensembl peptide - ENSP00000285116
Ensembl peptide - ENSP00000381470
NCBI entrez gene - 220134     See in Manteia.
OMIM - 616673
RefSeq - NM_145060
RefSeq - NM_001039535
RefSeq Peptide - NP_001034624
RefSeq Peptide - NP_659497
swissprot - Q96BD8
swissprot - K7EP61
swissprot - K7EPW0
swissprot - A0A024R294
Ensembl - ENSG00000154839
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ska1ENSDARG00000039354Danio rerio
 Ska1ENSMUSG00000036223Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009829  Spindle and kinetochore-associated protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0031110 regulation of microtubule polymerization or depolymerization IDA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0000940 condensed chromosome outer kinetochore IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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