ENSG00000154889


Homo sapiens

Features
Gene ID: ENSG00000154889
  
Biological name :MPPE1
  
Synonyms : metallophosphoesterase 1 / MPPE1 / Q53F39
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: p11.21
Gene start: 11882622
Gene end: 11909223
  
Corresponding Affymetrix probe sets: 206764_x_at (Human Genome U133 Plus 2.0 Array)   209858_x_at (Human Genome U133 Plus 2.0 Array)   213727_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468065
Ensembl peptide - ENSP00000467993
Ensembl peptide - ENSP00000468269
Ensembl peptide - ENSP00000468639
Ensembl peptide - ENSP00000468606
Ensembl peptide - ENSP00000311200
Ensembl peptide - ENSP00000312935
Ensembl peptide - ENSP00000327257
Ensembl peptide - ENSP00000339423
Ensembl peptide - ENSP00000433950
Ensembl peptide - ENSP00000464842
Ensembl peptide - ENSP00000465318
Ensembl peptide - ENSP00000465894
Ensembl peptide - ENSP00000466291
Ensembl peptide - ENSP00000466303
Ensembl peptide - ENSP00000467599
Ensembl peptide - ENSP00000467698
Ensembl peptide - ENSP00000467703
NCBI entrez gene - 65258     See in Manteia.
OMIM - 611900
RefSeq - XM_017025931
RefSeq - XM_006722343
RefSeq - XM_006722345
RefSeq - XM_006722346
RefSeq - XM_006722347
RefSeq - XM_006722348
RefSeq - XM_011525731
RefSeq - XM_011525732
RefSeq - XM_011525734
RefSeq - XM_017025920
RefSeq - XM_017025921
RefSeq - XM_017025922
RefSeq - XM_017025923
RefSeq - XM_017025924
RefSeq - XM_017025925
RefSeq - XM_017025926
RefSeq - XM_017025927
RefSeq - XM_017025928
RefSeq - XM_017025929
RefSeq - XM_017025930
RefSeq - NM_001242904
RefSeq - NM_001319154
RefSeq - NM_023075
RefSeq - XM_006722340
RefSeq - XM_006722341
RefSeq - XM_006722342
RefSeq Peptide - NP_075563
RefSeq Peptide - NP_001229833
RefSeq Peptide - NP_001306083
RefSeq Peptide - NP_001317492
swissprot - K7ELZ7
swissprot - K7EM03
swissprot - K7EQ70
swissprot - K7EQ74
swissprot - K7EQV4
swissprot - A0A0C4DH11
swissprot - K7ERI3
swissprot - K7ES91
swissprot - K7ESB8
swissprot - Q53F39
swissprot - A0A075B777
swissprot - K7ER13
swissprot - A0A0A0MR93
swissprot - K7EIQ0
swissprot - K7EJU0
Ensembl - ENSG00000154889
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mppe1ENSDARG00000045416Danio rerio
 MPPE1ENSGALG00000013794Gallus gallus
 Mppe1ENSMUSG00000062526Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR029052  Metallo-dependent phosphatase-like
 IPR033308  PGAP5/Cdc1/Ted1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006506 GPI anchor biosynthetic process IBA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005801 cis-Golgi network ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0070971 endoplasmic reticulum exit site ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008081 phosphoric diester hydrolase activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding ISS
 molecular_functionGO:0034235 GPI anchor binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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