ENSG00000159231


Homo sapiens

Features
Gene ID: ENSG00000159231
  
Biological name :CBR3
  
Synonyms : carbonyl reductase 3 / CBR3 / O75828
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.12
Gene start: 36134912
Gene end: 36146566
  
Corresponding Affymetrix probe sets: 205379_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000290354
NCBI entrez gene - 874     See in Manteia.
OMIM - 603608
RefSeq - NM_001236
RefSeq Peptide - NP_001227
swissprot - O75828
swissprot - V9HW40
Ensembl - ENSG00000159231
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbr1ENSDARG00000036587Danio rerio
 CBR1ENSGALG00000016027Gallus gallus
 Cbr3ENSMUSG00000022947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CBR1 / P16152 / carbonyl reductase 1ENSG0000015922871


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0042376 phylloquinone catabolic process IEA
 biological_processGO:0050890 cognition IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000253 3-keto sterol reductase activity IEA
 molecular_functionGO:0004090 carbonyl reductase (NADPH) activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0070402 NADPH binding IDA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr