ENSG00000159479


Homo sapiens

Features
Gene ID: ENSG00000159479
  
Biological name :MED8
  
Synonyms : MED8 / mediator complex subunit 8 / Q96G25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.2
Gene start: 43383917
Gene end: 43389808
  
Corresponding Affymetrix probe sets: 213126_at (Human Genome U133 Plus 2.0 Array)   213127_s_at (Human Genome U133 Plus 2.0 Array)   213696_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000290663
Ensembl peptide - ENSP00000361533
Ensembl peptide - ENSP00000361535
NCBI entrez gene - 112950     See in Manteia.
OMIM - 607956
RefSeq - NM_052877
RefSeq - NM_001001653
RefSeq - NM_201542
RefSeq Peptide - NP_001001653
RefSeq Peptide - NP_443109
RefSeq Peptide - NP_963836
swissprot - Q96G25
Ensembl - ENSG00000159479
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MED8ENSDARG00000114425Danio rerio
 MED8ENSGALG00000009993Gallus gallus
 Med8ENSMUSG00000006392Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019364  Mediator complex, subunit Med8, fungi/metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016592 mediator complex IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr