ENSG00000162704


Homo sapiens

Features
Gene ID: ENSG00000162704
  
Biological name :ARPC5
  
Synonyms : actin related protein 2/3 complex subunit 5 / ARPC5 / O15511
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.3
Gene start: 183620846
Gene end: 183635757
  
Corresponding Affymetrix probe sets: 1555797_a_at (Human Genome U133 Plus 2.0 Array)   1569325_at (Human Genome U133 Plus 2.0 Array)   211963_s_at (Human Genome U133 Plus 2.0 Array)   237387_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000294742
Ensembl peptide - ENSP00000356504
Ensembl peptide - ENSP00000352918
NCBI entrez gene - 10092     See in Manteia.
OMIM - 604227
RefSeq - NM_001270439
RefSeq - NM_005717
RefSeq Peptide - NP_001257368
RefSeq Peptide - NP_005708
swissprot - B1ALC0
swissprot - O15511
Ensembl - ENSG00000162704
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arpc5aENSDARG00000039142Danio rerio
 arpc5bENSDARG00000019062Danio rerio
 ARPC5ENSGALG00000020927Gallus gallus
 Arpc5ENSMUSG00000008475Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARPC5L / Q9BPX5 / actin related protein 2/3 complex subunit 5 likeENSG0000013695066


Protein motifs (from Interpro)
Interpro ID Name
 IPR006789  Actin-related protein 2/3 complex subunit 5
 IPR036743  Actin-related protein 2/3 complex subunit 5 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014909 smooth muscle cell migration IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0021769 orbitofrontal cortex development IEA
 biological_processGO:0030011 maintenance of cell polarity IEA
 biological_processGO:0030036 actin cytoskeleton organization TAS
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IDA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0051639 actin filament network formation IEA
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0061842 microtubule organizing center localization IEA
 biological_processGO:0097581 lamellipodium organization IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
Neutrophil degranulation
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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