ENSG00000162961


Homo sapiens

Features
Gene ID: ENSG00000162961
  
Biological name :DPY30
  
Synonyms : DPY30 / dpy-30, histone methyltransferase complex regulatory subunit / Q9C005
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p22.3
Gene start: 31867809
Gene end: 32039812
  
Corresponding Affymetrix probe sets: 1555522_s_at (Human Genome U133 Plus 2.0 Array)   219065_s_at (Human Genome U133 Plus 2.0 Array)   224129_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295066
Ensembl peptide - ENSP00000345837
NCBI entrez gene - 84661     See in Manteia.
OMIM - 612032
RefSeq - XM_006712117
RefSeq - NM_001321209
RefSeq - NM_032574
RefSeq Peptide - NP_115963
RefSeq Peptide - NP_001308138
swissprot - Q9C005
Ensembl - ENSG00000162961
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpy30ENSDARG00000004427Danio rerio
 DPY30ENSGALG00000010621Gallus gallus
 Dpy30ENSMUSG00000024067Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007858  Dpy-30 motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006348 chromatin silencing at telomere IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016197 endosomal transport IMP
 biological_processGO:0045652 regulation of megakaryocyte differentiation TAS
 biological_processGO:0051568 histone H3-K4 methylation IDA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0035097 histone methyltransferase complex IDA
 cellular_componentGO:0044666 MLL3/4 complex IDA
 cellular_componentGO:0048188 Set1C/COMPASS complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity TAS
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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