ENSG00000163273


Homo sapiens

Features
Gene ID: ENSG00000163273
  
Biological name :NPPC
  
Synonyms : natriuretic peptide C / NPPC / P23582
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q37.1
Gene start: 231921820
Gene end: 231926403
  
Corresponding Affymetrix probe sets: 221348_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295440
Ensembl peptide - ENSP00000387159
NCBI entrez gene - 4880     See in Manteia.
OMIM - 600296
RefSeq - XM_011511245
RefSeq - NM_024409
RefSeq Peptide - NP_077720
swissprot - P23582
Ensembl - ENSG00000163273
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nppcENSDARG00000068126Danio rerio
 NppcENSMUSG00000026241Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000663  Natriuretic peptide
 IPR002406  Natriuretic peptide, C type
 IPR030480  Natriuretic peptide, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0003418 growth plate cartilage chondrocyte differentiation ISS
 biological_processGO:0003419 growth plate cartilage chondrocyte proliferation ISS
 biological_processGO:0006182 cGMP biosynthetic process IDA
 biological_processGO:0006457 protein folding IDA
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway IDA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0022414 reproductive process IEA
 biological_processGO:0030814 obsolete regulation of cAMP metabolic process IDA
 biological_processGO:0030823 obsolete regulation of cGMP metabolic process IDA
 biological_processGO:0030828 obsolete positive regulation of cGMP biosynthetic process IEA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0048513 animal organ development IEA
 biological_processGO:0048660 regulation of smooth muscle cell proliferation IEA
 biological_processGO:0050880 regulation of blood vessel size IEA
 biological_processGO:0051053 negative regulation of DNA metabolic process IEA
 biological_processGO:0051447 negative regulation of meiotic cell cycle IDA
 biological_processGO:0097755 positive regulation of blood vessel diameter IEA
 biological_processGO:1900194 negative regulation of oocyte maturation IDA
 biological_processGO:1903779 regulation of cardiac conduction TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0051427 hormone receptor binding IPI
 molecular_functionGO:0051428 peptide hormone receptor binding IEA


Pathways (from Reactome)
Pathway description
Physiological factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000159899 NPR2 / P20594 / natriuretic peptide receptor 2  / complex / reaction






 

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