ENSG00000163655


Homo sapiens

Features
Gene ID: ENSG00000163655
  
Biological name :GMPS
  
Synonyms : GMPS / guanine monophosphate synthase / P49915
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q25.31
Gene start: 155870536
Gene end: 155944026
  
Corresponding Affymetrix probe sets: 214431_at (Human Genome U133 Plus 2.0 Array)   229333_at (Human Genome U133 Plus 2.0 Array)   236648_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419851
Ensembl peptide - ENSP00000295920
NCBI entrez gene - 8833     See in Manteia.
OMIM - 600358
RefSeq - XM_017007422
RefSeq - NM_003875
RefSeq - XM_011513263
RefSeq Peptide - NP_003866
swissprot - P49915
swissprot - A0A140VJK6
Ensembl - ENSG00000163655
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmpsENSDARG00000079848Danio rerio
 GMPSENSGALG00000010284Gallus gallus
 GmpsENSMUSG00000027823Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001674  GMP synthase, C-terminal
 IPR004739  GMP synthase, glutamine amidotransferase
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR017926  Glutamine amidotransferase
 IPR022310  NAD/GMP synthase
 IPR025777  GMP synthetase ATP pyrophosphatase domain
 IPR029062  Class I glutamine amidotransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006177 GMP biosynthetic process IBA
 biological_processGO:0006541 glutamine metabolic process IEA
 biological_processGO:0009113 purine nucleobase biosynthetic process TAS
 biological_processGO:0009168 purine ribonucleoside monophosphate biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003921 GMP synthase activity TAS
 molecular_functionGO:0003922 GMP synthase (glutamine-hydrolyzing) activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016462 pyrophosphatase activity IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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