ENSG00000163719


Homo sapiens

Features
Gene ID: ENSG00000163719
  
Biological name :MTMR14
  
Synonyms : MTMR14 / myotubularin related protein 14 / Q8NCE2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.3
Gene start: 9649433
Gene end: 9702393
  
Corresponding Affymetrix probe sets: 222143_s_at (Human Genome U133 Plus 2.0 Array)   232342_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401993
Ensembl peptide - ENSP00000392935
Ensembl peptide - ENSP00000408813
Ensembl peptide - ENSP00000412644
Ensembl peptide - ENSP00000411417
Ensembl peptide - ENSP00000410761
Ensembl peptide - ENSP00000296003
Ensembl peptide - ENSP00000323462
Ensembl peptide - ENSP00000334070
Ensembl peptide - ENSP00000388746
Ensembl peptide - ENSP00000392690
NCBI entrez gene - 64419     See in Manteia.
OMIM - 611089
RefSeq - XM_017007045
RefSeq - XM_011534013
RefSeq - XM_017007034
RefSeq - XM_017007035
RefSeq - XM_017007036
RefSeq - XM_017007037
RefSeq - XM_017007038
RefSeq - XM_017007039
RefSeq - XM_017007040
RefSeq - XM_017007041
RefSeq - XM_017007042
RefSeq - XM_017007043
RefSeq - XM_017007044
RefSeq - NM_001077525
RefSeq - NM_001077526
RefSeq - NM_022485
RefSeq - XM_005265400
RefSeq - XM_011534012
RefSeq Peptide - NP_071930
RefSeq Peptide - NP_001070993
RefSeq Peptide - NP_001070994
swissprot - F8WBT3
swissprot - F8WCC0
swissprot - F8WCG0
swissprot - C9JSR1
swissprot - Q8NCE2
swissprot - B4DJ23
swissprot - F8WEA3
swissprot - C9JR61
swissprot - B4DQK9
Ensembl - ENSG00000163719
  
Related genetic diseases (OMIM): 160150 - {Centronuclear myopathy, autosomal, modifier of}, 160150
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtmr14ENSDARG00000059642Danio rerio
 MTMR14ENSGALG00000006601Gallus gallus
 Mtmr14ENSMUSG00000030269Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010569  Myotubularin-like phosphatase domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity IDA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity TAS
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity TAS


Pathways (from Reactome)
Pathway description
Macroautophagy
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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