ENSG00000163803


Homo sapiens

Features
Gene ID: ENSG00000163803
  
Biological name :PLB1
  
Synonyms : phospholipase B1 / PLB1 / Q6P1J6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p23.2
Gene start: 28457145
Gene end: 28643788
  
Corresponding Affymetrix probe sets: 1553310_at (Human Genome U133 Plus 2.0 Array)   235703_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000407076
Ensembl peptide - ENSP00000404723
Ensembl peptide - ENSP00000416440
Ensembl peptide - ENSP00000330442
Ensembl peptide - ENSP00000384187
Ensembl peptide - ENSP00000391810
Ensembl peptide - ENSP00000392493
Ensembl peptide - ENSP00000399712
NCBI entrez gene - 151056     See in Manteia.
OMIM - 610179
RefSeq - XM_017003434
RefSeq - XM_011532593
RefSeq - XM_011532601
RefSeq - XM_011532602
RefSeq - XM_011532603
RefSeq - XM_011532606
RefSeq - XM_011532607
RefSeq - XM_011532609
RefSeq - XM_017003432
RefSeq - XM_017003433
RefSeq - NM_001170585
RefSeq - NM_153021
RefSeq - XM_011532579
RefSeq - XM_011532581
RefSeq - XM_011532584
RefSeq - XM_011532588
RefSeq - XM_011532589
RefSeq - XM_011532590
RefSeq - XM_011532591
RefSeq Peptide - NP_001164056
RefSeq Peptide - NP_694566
swissprot - H7C012
swissprot - H7C1D3
swissprot - H7BYX7
swissprot - Q6P1J6
swissprot - C9JYQ2
swissprot - H7C2A5
swissprot - H7BZW4
Ensembl - ENSG00000163803
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-214p16.3ENSDARG00000096445Danio rerio
 ENSGALG00000029862Gallus gallus
 Plb1ENSMUSG00000029134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001087  GDSL lipase/esterase
 IPR008265  Lipase, GDSL, active site
 IPR035547  Phospholipase B
 IPR036514  SGNH hydrolase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process TAS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0036151 phosphatidylcholine acyl-chain remodeling TAS
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:2000344 positive regulation of acrosome reaction IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0004622 lysophospholipase activity IEA
 molecular_functionGO:0004623 phospholipase A2 activity TAS
 molecular_functionGO:0016298 lipase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IEA
 molecular_functionGO:0050253 retinyl-palmitate esterase activity TAS
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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