ENSG00000164978


Homo sapiens

Features
Gene ID: ENSG00000164978
  
Biological name :NUDT2
  
Synonyms : nudix hydrolase 2 / NUDT2 / P50583
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p13.3
Gene start: 34329506
Gene end: 34343713
  
Corresponding Affymetrix probe sets: 218609_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000344187
Ensembl peptide - ENSP00000368452
Ensembl peptide - ENSP00000368455
Ensembl peptide - ENSP00000482384
NCBI entrez gene - 318     See in Manteia.
OMIM - 602852
RefSeq - NM_001244390
RefSeq - NM_001161
RefSeq - NM_147172
RefSeq - NM_147173
RefSeq Peptide - NP_001152
RefSeq Peptide - NP_001231319
RefSeq Peptide - NP_671701
RefSeq Peptide - NP_671702
swissprot - P50583
Ensembl - ENSG00000164978
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt2ENSDARG00000058728Danio rerio
 NUDT2ENSGALG00000027295Gallus gallus
 Nudt2ENSMUSG00000028443Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR003565  Bis(5"-nucleosyl)-tetraphosphatase
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process TAS
 biological_processGO:0006915 apoptotic process ISS
 biological_processGO:0034599 cellular response to oxidative stress TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004081 bis(5"-nucleosyl)-tetraphosphatase (asymmetrical) activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008796 bis(5"-nucleosyl)-tetraphosphatase activity IEA
 molecular_functionGO:0008803 bis(5"-nucleosyl)-tetraphosphatase (symmetrical) activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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