ENSG00000166192


Homo sapiens

Features
Gene ID: ENSG00000166192
  
Biological name :SENP8
  
Synonyms : Q96LD8 / SENP8 / SUMO/sentrin peptidase family member, NEDD8 specific
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q23
Gene start: 72114258
Gene end: 72143688
  
Corresponding Affymetrix probe sets: 1552684_a_at (Human Genome U133 Plus 2.0 Array)   228398_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446057
Ensembl peptide - ENSP00000457208
Ensembl peptide - ENSP00000457215
Ensembl peptide - ENSP00000340505
Ensembl peptide - ENSP00000456567
NCBI entrez gene - 123228     See in Manteia.
OMIM - 608659
RefSeq - XM_011521217
RefSeq - NM_001166340
RefSeq - NM_001172109
RefSeq - NM_001172110
RefSeq - NM_001172111
RefSeq - NM_145204
RefSeq - XM_005254157
RefSeq Peptide - NP_001165581
RefSeq Peptide - NP_001165582
RefSeq Peptide - NP_660205
RefSeq Peptide - NP_001159812
RefSeq Peptide - NP_001165580
swissprot - Q96LD8
swissprot - H3BTJ8
swissprot - H3BTK5
swissprot - H3BS71
Ensembl - ENSG00000166192
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 senp8ENSDARG00000019595Danio rerio
 SENP8ENSGALG00000027050Gallus gallus
 Senp8ENSMUSG00000051705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003653  Ulp1 protease family, C-terminal catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0016926 protein desumoylation IBA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004175 endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019784 NEDD8-specific protease activity TAS


Pathways (from Reactome)
Pathway description
UCH proteinases
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129559 NEDD8 / Q15843 / neural precursor cell expressed, developmentally down-regulated 8  / complex






 

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