ENSG00000166451


Homo sapiens

Features
Gene ID: ENSG00000166451
  
Biological name :CENPN
  
Synonyms : CENPN / centromere protein N / Q96H22
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q23.2
Gene start: 81006498
Gene end: 81033114
  
Corresponding Affymetrix probe sets: 219555_s_at (Human Genome U133 Plus 2.0 Array)   222118_at (Human Genome U133 Plus 2.0 Array)   234811_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456413
Ensembl peptide - ENSP00000454327
Ensembl peptide - ENSP00000454337
Ensembl peptide - ENSP00000299572
Ensembl peptide - ENSP00000305608
Ensembl peptide - ENSP00000377007
Ensembl peptide - ENSP00000393991
Ensembl peptide - ENSP00000395235
NCBI entrez gene - 55839     See in Manteia.
OMIM - 611509
RefSeq - XM_017023456
RefSeq - NM_001100624
RefSeq - NM_001100625
RefSeq - NM_001270473
RefSeq - NM_001270474
RefSeq - NM_018455
RefSeq - XM_006721236
RefSeq Peptide - NP_001257402
RefSeq Peptide - NP_001257403
RefSeq Peptide - NP_060925
RefSeq Peptide - NP_001094094
RefSeq Peptide - NP_001094095
swissprot - Q96H22
swissprot - H3BMD5
swissprot - H3BRU7
swissprot - H3BMC7
Ensembl - ENSG00000166451
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cenpnENSDARG00000043640Danio rerio
 CENPNENSGALG00000013494Gallus gallus
 CenpnENSMUSG00000031756Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007902  Centromere protein Chl4/mis15/CENP-N


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0034080 CENP-A containing nucleosome assembly TAS
 biological_processGO:0034508 centromere complex assembly IEA
 biological_processGO:0051382 kinetochore assembly IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol TAS


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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