ENSG00000166562


Homo sapiens

Features
Gene ID: ENSG00000166562
  
Biological name :SEC11C
  
Synonyms : Q9BY50 / SEC11C / SEC11 homolog C, signal peptidase complex subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.32
Gene start: 59139477
Gene end: 59158836
  
Corresponding Affymetrix probe sets: 223299_at (Human Genome U133 Plus 2.0 Array)   235676_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468633
Ensembl peptide - ENSP00000482872
Ensembl peptide - ENSP00000299714
Ensembl peptide - ENSP00000465281
NCBI entrez gene - 90701     See in Manteia.
RefSeq - XM_017026073
RefSeq - NM_001307941
RefSeq - NM_033280
RefSeq - XM_011526260
RefSeq Peptide - NP_001294870
RefSeq Peptide - NP_150596
swissprot - A0A0A0MR04
swissprot - B4DI03
swissprot - K7EJQ7
swissprot - Q9BY50
Ensembl - ENSG00000166562
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SEC11CENSGALG00000031663Gallus gallus
 Q9D8V7ENSMUSG00000024516Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P67812 / SEC11A / SEC11 homolog A, signal peptidase complex subunitENSG0000014061264


Protein motifs (from Interpro)
Interpro ID Name
 IPR001733  Peptidase S26B
 IPR015927  Peptidase S24/S26A/S26B/S26C
 IPR019756  Peptidase S26A, signal peptidase I, serine active site
 IPR019758  Peptidase S26A, signal peptidase I, conserved site
 IPR036286  LexA/Signal peptidase-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006465 signal peptide processing IEA
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005787 signal peptidase complex IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
SRP-dependent cotranslational protein targeting to membrane
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
Synthesis, secretion, and deacylation of Ghrelin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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