ENSG00000167393


Homo sapiens

Features
Gene ID: ENSG00000167393
  
Biological name :PPP2R3B
  
Synonyms : PPP2R3B / protein phosphatase 2 regulatory subunit Bbeta / Q9Y5P8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.33
Gene start: 333963
Gene end: 386955
  
Corresponding Affymetrix probe sets: 1566630_at (Human Genome U133 Plus 2.0 Array)   219264_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000371038
Ensembl peptide - ENSP00000375080
NCBI entrez gene - 28227     See in Manteia.
OMIM - 300339
RefSeq - NM_013239
RefSeq - XM_011546177
RefSeq Peptide - NP_037371
swissprot - C9JMU6
swissprot - Q9Y5P8
Ensembl - ENSG00000167393
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp2r3bENSDARG00000076004Danio rerio
 PPP2R3BENSGALG00000016702Gallus gallus
 Ppp2r3dENSMUSG00000093803Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q06190 / PPP2R3A / protein phosphatase 2 regulatory subunit BalphaENSG0000007371149
Q969Q6 / PPP2R3C / protein phosphatase 2 regulatory subunit BgammaENSG0000009202014


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation ISS
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex ISS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0004721 phosphoprotein phosphatase activity TAS
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity ISS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019888 protein phosphatase regulator activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Inhibition of replication initiation of damaged DNA by RB1/E2F1
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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