ENSG00000167851


Homo sapiens

Features
Gene ID: ENSG00000167851
  
Biological name :CD300A
  
Synonyms : CD300A / CD300a molecule / Q9UGN4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.1
Gene start: 74466416
Gene end: 74484796
  
Corresponding Affymetrix probe sets: 209933_s_at (Human Genome U133 Plus 2.0 Array)   217072_at (Human Genome U133 Plus 2.0 Array)   217078_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000353259
Ensembl peptide - ENSP00000376401
Ensembl peptide - ENSP00000463189
Ensembl peptide - ENSP00000308188
Ensembl peptide - ENSP00000354564
NCBI entrez gene - 11314     See in Manteia.
OMIM - 606790
RefSeq - XM_011524254
RefSeq - NM_001256841
RefSeq - NM_007261
RefSeq - XM_005256990
RefSeq - XM_005256991
RefSeq - XM_005256992
RefSeq - XM_006721656
RefSeq Peptide - NP_001243770
RefSeq Peptide - NP_001317385
RefSeq Peptide - NP_001317386
RefSeq Peptide - NP_009192
swissprot - Q9UGN4
swissprot - J3QKQ4
Ensembl - ENSG00000167851
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD300LGENSGALG00000007713Gallus gallus
 CD300L-S1ENSGALG00000019755Gallus gallus
 Cd300aENSMUSG00000034652Mus musculus
 Cd300cENSMUSG00000058728Mus musculus
 Q7TSN2ENSMUSG00000044811Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD300C / Q08708 / CD300c moleculeENSG0000016785045
Q8TDQ1 / CD300LF / CD300 molecule like family member fENSG0000018607431
CD300E / Q496F6 / CD300e moleculeENSG0000018640727
AC079325.2ENSG0000028469027
A8K4G0 / CD300LB / CD300 molecule like family member bENSG0000017878923
Q6UXZ3 / CD300LD / CD300 molecule like family member dENSG0000020434523
Q6UXG3 / CD300LG / CD300 molecule like family member gENSG0000016164922


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030889 negative regulation of B cell proliferation IMP
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity IDA
 biological_processGO:0033007 negative regulation of mast cell activation involved in immune response IDA
 biological_processGO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway IMP
 biological_processGO:0043305 negative regulation of mast cell degranulation IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043407 negative regulation of MAP kinase activity IDA
 biological_processGO:0048147 negative regulation of fibroblast proliferation IDA
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0050856 regulation of T cell receptor signaling pathway IDA
 biological_processGO:0050859 negative regulation of B cell receptor signaling pathway IDA
 biological_processGO:0051134 negative regulation of NK T cell activation IDA
 biological_processGO:0060101 negative regulation of phagocytosis, engulfment IMP
 biological_processGO:1902564 negative regulation of neutrophil activation IDA
 biological_processGO:1902567 negative regulation of eosinophil activation IDA
 biological_processGO:1902569 negative regulation of activation of Janus kinase activity IDA
 biological_processGO:2000417 negative regulation of eosinophil migration IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008429 phosphatidylethanolamine binding IDA
 molecular_functionGO:0038023 signaling receptor activity IDA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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