ENSG00000168081


Homo sapiens

Features
Gene ID: ENSG00000168081
  
Biological name :PNOC
  
Synonyms : PNOC / prepronociceptin / Q13519
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p21.1
Gene start: 28316986
Gene end: 28343355
  
Corresponding Affymetrix probe sets: 205901_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430145
Ensembl peptide - ENSP00000301908
Ensembl peptide - ENSP00000428059
NCBI entrez gene - 5368     See in Manteia.
OMIM - 601459
RefSeq - XM_017013578
RefSeq - NM_001284244
RefSeq - NM_006228
RefSeq - XM_005273532
RefSeq - XM_011544559
RefSeq Peptide - NP_001271173
RefSeq Peptide - NP_006219
swissprot - Q13519
swissprot - E7EVP0
Ensembl - ENSG00000168081
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pnocaENSDARG00000025024Danio rerio
 pnocbENSDARG00000024189Danio rerio
 PNOCENSGALG00000016620Gallus gallus
 PnocENSMUSG00000045731Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002367  Nociceptin
 IPR006024  Opioid neuropeptide precursor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007600 sensory perception TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0030425 dendrite IBA
 cellular_componentGO:0043025 neuronal cell body IBA
 cellular_componentGO:0043679 axon terminus IBA
 molecular_functionGO:0001515 opioid peptide activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity TAS
 molecular_functionGO:0031628 opioid receptor binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125510 OPRL1 / P41146 / opioid related nociceptin receptor 1  / complex / reaction






 

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