ENSG00000168421


Homo sapiens

Features
Gene ID: ENSG00000168421
  
Biological name :RHOH
  
Synonyms : Q15669 / ras homolog family member H / RHOH
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p14
Gene start: 40191053
Gene end: 40246967
  
Corresponding Affymetrix probe sets: 204951_at (Human Genome U133 Plus 2.0 Array)   236293_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481566
Ensembl peptide - ENSP00000480772
Ensembl peptide - ENSP00000481746
Ensembl peptide - ENSP00000482947
Ensembl peptide - ENSP00000481836
Ensembl peptide - ENSP00000371219
Ensembl peptide - ENSP00000420866
Ensembl peptide - ENSP00000422241
Ensembl peptide - ENSP00000423384
Ensembl peptide - ENSP00000425010
Ensembl peptide - ENSP00000426439
Ensembl peptide - ENSP00000478248
Ensembl peptide - ENSP00000480192
Ensembl peptide - ENSP00000480379
NCBI entrez gene - 399     See in Manteia.
OMIM - 602037
RefSeq - NM_004310
RefSeq - NM_001278359
RefSeq - NM_001278360
RefSeq - NM_001278361
RefSeq - NM_001278362
RefSeq - NM_001278363
RefSeq - NM_001278364
RefSeq - NM_001278365
RefSeq - NM_001278366
RefSeq - NM_001278367
RefSeq - NM_001278368
RefSeq - NM_001278369
RefSeq - XM_011513692
RefSeq - XM_017008188
RefSeq - XM_017008189
RefSeq Peptide - NP_001265288
RefSeq Peptide - NP_001265289
RefSeq Peptide - NP_001265290
RefSeq Peptide - NP_001265295
RefSeq Peptide - NP_001265296
RefSeq Peptide - NP_001265297
RefSeq Peptide - NP_001265298
RefSeq Peptide - NP_004301
RefSeq Peptide - NP_001265291
RefSeq Peptide - NP_001265292
RefSeq Peptide - NP_001265293
RefSeq Peptide - NP_001265294
swissprot - D6RG23
swissprot - D6RA52
swissprot - Q15669
swissprot - Q6ICP4
swissprot - D6R8Z1
Ensembl - ENSG00000168421
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhohENSDARG00000070121Danio rerio
 ENSGALG00000014277Gallus gallus
 RhohENSMUSG00000029204Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0030217 T cell differentiation NAS
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0042326 negative regulation of phosphorylation IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0045576 mast cell activation IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005095 GTPase inhibitor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0017048 Rho GTPase binding NAS
 molecular_functionGO:0019210 kinase inhibitor activity IDA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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