ENSG00000168434


Homo sapiens

Features
Gene ID: ENSG00000168434
  
Biological name :COG7
  
Synonyms : COG7 / component of oligomeric golgi complex 7 / P83436
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.2
Gene start: 23388493
Gene end: 23453180
  
Corresponding Affymetrix probe sets: 213190_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460151
Ensembl peptide - ENSP00000305442
Ensembl peptide - ENSP00000459872
NCBI entrez gene - 91949     See in Manteia.
OMIM - 606978
RefSeq - XM_017023870
RefSeq - NM_153603
RefSeq Peptide - NP_705831
swissprot - I3L337
swissprot - A0A0S2Z652
swissprot - P83436
swissprot - I3L2R8
Ensembl - ENSG00000168434
  
Related genetic diseases (OMIM): 608779 - Congenital disorder of glycosylation, type IIe, 608779
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cog7ENSDARG00000061372Danio rerio
 COG7ENSGALG00000006156Gallus gallus
 Cog7ENSMUSG00000034951Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019335  Conserved oligomeric Golgi complex subunit 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IMP
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IMP
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0033365 protein localization to organelle IMP
 biological_processGO:0034067 protein localization to Golgi apparatus IMP
 biological_processGO:0050821 protein stabilization IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0017119 Golgi transport complex IEA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0001252 Muscular hypotonia "Muscular hypotonia is an abnormally low muscle tone (the amount of tension or resistance to movement in a muscle), often involving reduced muscle strength. Hypotonia is characterized by a diminished resistance to passive stretching." [HPO:curators]
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 HP:0001639 Hypertrophic cardiomyopathy 
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 HP:0010978 Abnormality of immune system physiology "A functional abnormality of the `immune system` (FMA:9825)." [HPO:probinson, MP:0001790]
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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