ENSG00000168495


Homo sapiens

Features
Gene ID: ENSG00000168495
  
Biological name :POLR3D
  
Synonyms : P05423 / POLR3D / RNA polymerase III subunit D
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p21.3
Gene start: 22245104
Gene end: 22254600
  
Corresponding Affymetrix probe sets: 208361_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000380904
Ensembl peptide - ENSP00000429821
Ensembl peptide - ENSP00000429677
Ensembl peptide - ENSP00000303088
NCBI entrez gene - 661     See in Manteia.
OMIM - 187280
RefSeq - NM_001722
RefSeq Peptide - NP_001713
swissprot - E7EQ68
swissprot - E5RHT4
swissprot - P05423
Ensembl - ENSG00000168495
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Polr3dENSMUSG00000000776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007811  DNA-directed RNA polymerase III subunit RPC4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0032728 positive regulation of interferon-beta production IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response IDA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA


Pathways (from Reactome)
Pathway description
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000058600 POLR3E / Q9NVU0 / RNA polymerase III subunit E  / complex






 

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