ENSG00000168936


Homo sapiens

Features
Gene ID: ENSG00000168936
  
Biological name :TMEM129
  
Synonyms : A0AVI4 / TMEM129 / transmembrane protein 129
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.3
Gene start: 1715952
Gene end: 1721358
  
Corresponding Affymetrix probe sets: 225587_at (Human Genome U133 Plus 2.0 Array)   225588_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000305243
Ensembl peptide - ENSP00000417259
Ensembl peptide - ENSP00000417412
Ensembl peptide - ENSP00000441812
Ensembl peptide - ENSP00000372394
NCBI entrez gene - 92305     See in Manteia.
OMIM - 615975
RefSeq - XM_017008834
RefSeq - NM_001127266
RefSeq - NM_138385
RefSeq - XM_005248038
RefSeq - XM_005248039
RefSeq - XM_011513594
RefSeq Peptide - NP_612394
RefSeq Peptide - NP_001120738
swissprot - H7C4G7
swissprot - H7C4I8
swissprot - A0AVI4
Ensembl - ENSG00000168936
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem129ENSDARG00000075346Danio rerio
 TMEM129ENSGALG00000015710Gallus gallus
 Q8K304ENSMUSG00000019295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018801  E3 ubiquitin-protein ligase TM129


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IMP
 biological_processGO:0030970 retrograde protein transport, ER to cytosol IMP
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity EXP


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr