ENSG00000169876


Homo sapiens

Features
Gene ID: ENSG00000169876
  
Biological name :MUC17
  
Synonyms : MUC17 / mucin 17, cell surface associated / Q685J3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 101020072
Gene end: 101058745
  
Corresponding Affymetrix probe sets: 232321_at (Human Genome U133 Plus 2.0 Array)   232407_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302716
Ensembl peptide - ENSP00000368751
NCBI entrez gene - 140453     See in Manteia.
OMIM - 608424
RefSeq - NM_001040105
RefSeq Peptide - NP_001035194
swissprot - E7EPM4
swissprot - Q685J3
Ensembl - ENSG00000169876
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-196f2.3ENSDARG00000105522Danio rerio
 Muc3ENSMUSG00000037390Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MUC12 / Q9UKN1 / mucin 12, cell surface associatedENSG0000020527716
MUC3A / Q02505 / mucin 3A, cell surface associatedENSG0000016989413


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR000742  EGF-like domain
 IPR013032  EGF-like, conserved site
 IPR036364  SEA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0019725 cellular homeostasis TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding IPI
 molecular_functionGO:0030197 extracellular matrix constituent, lubricant activity NAS


Pathways (from Reactome)
Pathway description
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
Defective GALNT12 causes colorectal cancer 1 (CRCS1)
Dectin-2 family
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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