ENSG00000170855


Homo sapiens

Features
Gene ID: ENSG00000170855
  
Biological name :TRIAP1
  
Synonyms : O43715 / TP53 regulated inhibitor of apoptosis 1 / TRIAP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.31
Gene start: 120443961
Gene end: 120446412
  
Corresponding Affymetrix probe sets: 218403_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449795
NCBI entrez gene - 51499     See in Manteia.
OMIM - 614943
RefSeq - NM_016399
RefSeq Peptide - NP_057483
swissprot - O43715
Ensembl - ENSG00000170855
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 triap1ENSDARG00000014963Danio rerio
 TRIAP1ENSGALG00000007199Gallus gallus
 Q9D8Z2ENSMUSG00000029535Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007918  Mitochondrial distribution/morphology family 35/apoptosis


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0015914 phospholipid transport IDA
 biological_processGO:0030330 DNA damage response, signal transduction by p53 class mediator IDA
 biological_processGO:0034644 cellular response to UV IDA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0090201 negative regulation of release of cytochrome c from mitochondria IMP
 biological_processGO:0097035 regulation of membrane lipid distribution IMP
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:2001140 positive regulation of phospholipid transport IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005758 mitochondrial intermembrane space TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:1990050 phosphatidic acid transporter activity IDA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000169230 Q9Y255 / PRELID1 / PRELI domain containing 1  / reaction / complex






 

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