ENSG00000171124


Homo sapiens

Features
Gene ID: ENSG00000171124
  
Biological name :FUT3
  
Synonyms : fucosyltransferase 3 (Lewis blood group) / FUT3 / P21217
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 5842888
Gene end: 5851474
  
Corresponding Affymetrix probe sets: 214088_s_at (Human Genome U133 Plus 2.0 Array)   216010_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468795
Ensembl peptide - ENSP00000468123
Ensembl peptide - ENSP00000468515
Ensembl peptide - ENSP00000305603
Ensembl peptide - ENSP00000416443
Ensembl peptide - ENSP00000465804
Ensembl peptide - ENSP00000467081
Ensembl peptide - ENSP00000467633
NCBI entrez gene - 2525     See in Manteia.
OMIM - 111100
RefSeq - XM_011527867
RefSeq - NM_000149
RefSeq - NM_001097639
RefSeq - NM_001097640
RefSeq - NM_001097641
RefSeq - XM_011527865
RefSeq - XM_011527866
RefSeq Peptide - NP_000140
RefSeq Peptide - NP_001091108
RefSeq Peptide - NP_001091109
RefSeq Peptide - NP_001091110
swissprot - P21217
swissprot - K7ENT3
swissprot - K7EQ20
swissprot - K7ES24
Ensembl - ENSG00000171124
  
Related genetic diseases (OMIM): 111100 - [Blood group, Lewis]
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000001806Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FUT5 / Q11128 / fucosyltransferase 5ENSG0000013038391
FUT6 / P51993 / fucosyltransferase 6ENSG0000015641384
FUT4 / P22083 / fucosyltransferase 4ENSG0000019637142
FUT7 / Q11130 / fucosyltransferase 7ENSG0000018054937
FUT9 / Q9Y231 / fucosyltransferase 9ENSG0000017246137
FUT10 / Q6P4F1 / fucosyltransferase 10ENSG0000017272825
FUT11 / Q495W5 / fucosyltransferase 11ENSG0000019696825


Protein motifs (from Interpro)
Interpro ID Name
 IPR001503  Glycosyl transferase family 10
 IPR031481  Fucosyltransferase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006672 ceramide metabolic process IDA
 biological_processGO:0009312 oligosaccharide biosynthetic process IDA
 biological_processGO:0009988 cell-cell recognition IC
 biological_processGO:0036065 fucosylation IEA
 biological_processGO:0043413 macromolecule glycosylation IDA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008417 fucosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity TAS
 molecular_functionGO:0046920 alpha-(1->3)-fucosyltransferase activity IDA


Pathways (from Reactome)
Pathway description
Reactions specific to the complex N-glycan synthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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