ENSG00000172661


Homo sapiens

Features
Gene ID: ENSG00000172661
  
Biological name :WASHC2C
  
Synonyms : Q9Y4E1 / WASHC2C / WASH complex subunit 2C
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q11.22
Gene start: 45727200
Gene end: 45792961
  
Corresponding Affymetrix probe sets: 211068_x_at (Human Genome U133 Plus 2.0 Array)   212370_x_at (Human Genome U133 Plus 2.0 Array)   212929_s_at (Human Genome U133 Plus 2.0 Array)   214946_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416630
Ensembl peptide - ENSP00000363482
Ensembl peptide - ENSP00000439811
Ensembl peptide - ENSP00000485513
Ensembl peptide - ENSP00000442128
Ensembl peptide - ENSP00000337541
Ensembl peptide - ENSP00000352922
NCBI entrez gene - 253725     See in Manteia.
OMIM - 613631
RefSeq - XM_017016026
RefSeq - XM_017016017
RefSeq - XM_017016018
RefSeq - XM_017016019
RefSeq - XM_017016020
RefSeq - XM_017016021
RefSeq - XM_017016022
RefSeq - XM_017016023
RefSeq - XM_017016024
RefSeq - XM_017016025
RefSeq - NM_001169106
RefSeq - NM_001169107
RefSeq - NM_001330074
RefSeq - NM_015262
RefSeq - XM_011539566
RefSeq - XM_011539567
RefSeq - XM_011539568
RefSeq - XM_011539569
RefSeq - XM_011539570
RefSeq - XM_011539571
RefSeq - XM_011539572
RefSeq - XM_017016014
RefSeq - XM_017016015
RefSeq - XM_017016016
RefSeq Peptide - NP_001162578
RefSeq Peptide - NP_001317003
RefSeq Peptide - NP_056077
RefSeq Peptide - NP_001162577
swissprot - A0A0A0MT65
swissprot - Q9Y4E1
swissprot - A0A0A0MR88
swissprot - J3KP36
swissprot - A0A096LPC5
Ensembl - ENSG00000172661
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 washc2cENSDARG00000062532Danio rerio
 WASHC2CENSGALG00000005914Gallus gallus
 Q6PGL7ENSMUSG00000024104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q641Q2 / WASHC2A / WASH complex subunit 2AENSG0000009929099


Protein motifs (from Interpro)
Interpro ID Name
 IPR027308  WASH complex subunit 2
 IPR029341  FAM21/CAPZIP domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:1900024 regulation of substrate adhesion-dependent cell spreading IDA
 biological_processGO:1990126 retrograde transport, endosome to plasma membrane IMP
 biological_processGO:2000813 negative regulation of barbed-end actin filament capping IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030904 retromer complex IDA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0071203 WASH complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IDA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IDA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IDA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IDA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IDA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IDA
 molecular_functionGO:1905394 retromer complex binding IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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