ENSG00000172716


Homo sapiens

Features
Gene ID: ENSG00000172716
  
Biological name :SLFN11
  
Synonyms : Q7Z7L1 / schlafen family member 11 / SLFN11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 35350305
Gene end: 35373701
  
Corresponding Affymetrix probe sets: 226743_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465198
Ensembl peptide - ENSP00000464806
Ensembl peptide - ENSP00000465777
Ensembl peptide - ENSP00000468602
Ensembl peptide - ENSP00000468095
Ensembl peptide - ENSP00000312402
Ensembl peptide - ENSP00000378067
Ensembl peptide - ENSP00000393615
Ensembl peptide - ENSP00000395140
Ensembl peptide - ENSP00000397454
NCBI entrez gene - 91607     See in Manteia.
OMIM - 614953
RefSeq - XM_017025299
RefSeq - NM_001104587
RefSeq - NM_001104588
RefSeq - NM_001104589
RefSeq - NM_001104590
RefSeq - NM_152270
RefSeq - XM_005258068
RefSeq - XM_006722171
RefSeq - XM_011525465
RefSeq Peptide - NP_001098060
RefSeq Peptide - NP_689483
RefSeq Peptide - NP_001098057
RefSeq Peptide - NP_001098058
RefSeq Peptide - NP_001098059
swissprot - K7ES87
swissprot - C9JUT2
swissprot - C9JDG6
swissprot - K7EIM3
swissprot - K7EJJ3
swissprot - K7EKT7
swissprot - Q7Z7L1
swissprot - C9J902
swissprot - K7ER38
Ensembl - ENSG00000172716
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Slfn8ENSMUSG00000035208Mus musculus
 Slfn9ENSMUSG00000069793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q68D06 / SLFN13 / schlafen family member 13ENSG0000015476076
SLFN5 / Q08AF3 / schlafen family member 5ENSG0000016675051
P0C7P3 / SLFN14 / schlafen family member 14ENSG0000023632043
Q8IYM2 / SLFN12 / schlafen family member 12ENSG0000017212325
Q6IEE8 / SLFN12L / schlafen family member 12 likeENSG0000020504524


Protein motifs (from Interpro)
Interpro ID Name
 IPR007421  Schlafen, AAA domain
 IPR018647  Domain of unknown function DUF2075
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029682  Schlafen family member 11
 IPR029684  Schlafen family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016235 aggresome IDA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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