ENSG00000174177


Homo sapiens

Features
Gene ID: ENSG00000174177
  
Biological name :CTU2
  
Synonyms : CTU2 / cytosolic thiouridylase subunit 2 / Q2VPK5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q24.3
Gene start: 88706463
Gene end: 88715386
  
Corresponding Affymetrix probe sets: 226410_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456908
Ensembl peptide - ENSP00000455010
Ensembl peptide - ENSP00000455305
Ensembl peptide - ENSP00000308617
Ensembl peptide - ENSP00000388320
Ensembl peptide - ENSP00000454923
NCBI entrez gene - 348180     See in Manteia.
OMIM - 617057
RefSeq - XM_017023210
RefSeq - NM_001012759
RefSeq - NM_001012762
RefSeq - NM_001318507
RefSeq - NM_001318513
RefSeq Peptide - NP_001305436
RefSeq Peptide - NP_001012777
RefSeq Peptide - NP_001012780
RefSeq Peptide - NP_001305442
swissprot - H3BSW6
swissprot - H3BNU5
swissprot - Q2VPK5
swissprot - H3BNM3
swissprot - H3BPG4
Ensembl - ENSG00000174177
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctu2ENSDARG00000051851Danio rerio
 Ctu2ENSMUSG00000049482Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR019407  Cytoplasmic tRNA 2-thiolation protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002098 tRNA wobble uridine modification IEA
 biological_processGO:0002143 tRNA wobble position uridine thiolation IBA
 biological_processGO:0006400 tRNA modification TAS
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0032447 protein urmylation IEA
 biological_processGO:0034227 tRNA thio-modification IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0016783 sulfurtransferase activity IBA


Pathways (from Reactome)
Pathway description
tRNA modification in the nucleus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167118 URM1 / Q9BTM9 / ubiquitin related modifier 1  / complex
 ENSG00000142544 CTU1 / Q7Z7A3 / cytosolic thiouridylase subunit 1  / complex






 

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