ENSG00000175600


Homo sapiens

Features
Gene ID: ENSG00000175600
  
Biological name :SUGCT
  
Synonyms : Q9HAC7 / succinyl-CoA:glutarate-CoA transferase / SUGCT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p14.1
Gene start: 40134977
Gene end: 40860763
  
Corresponding Affymetrix probe sets: 219655_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486291
Ensembl peptide - ENSP00000395000
Ensembl peptide - ENSP00000401187
Ensembl peptide - ENSP00000338475
Ensembl peptide - ENSP00000385222
Ensembl peptide - ENSP00000393032
NCBI entrez gene - 79783     See in Manteia.
OMIM - 609187
RefSeq - XM_017012622
RefSeq - XM_006715775
RefSeq - XM_011515525
RefSeq - XM_011515526
RefSeq - XM_011515527
RefSeq - XM_011515528
RefSeq - XM_011515529
RefSeq - XM_011515530
RefSeq - XM_017012621
RefSeq - NM_001193311
RefSeq - NM_001193312
RefSeq - NM_001193313
RefSeq - NM_024728
RefSeq Peptide - NP_001180242
RefSeq Peptide - NP_079004
RefSeq Peptide - NP_001180240
RefSeq Peptide - NP_001180241
swissprot - Q9HAC7
swissprot - H7C1N0
swissprot - H7C0H3
swissprot - H0Y4N1
Ensembl - ENSG00000175600
  
Related genetic diseases (OMIM): 231690 - Glutaric aciduria III, 231690
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sugctENSDARG00000102341Danio rerio
 SUGCTENSGALG00000031758Gallus gallus
 SugctENSMUSG00000055137Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMACR / Q9UHK6 / alpha-methylacyl-CoA racemaseENSG0000024211020


Protein motifs (from Interpro)
Interpro ID Name
 IPR003673  CoA-transferase family III
 IPR017659  Formyl-CoA:oxalate CoA-transferase
 IPR023606  CoA-transferase family III domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0033608 formyl-CoA transferase activity IEA
 molecular_functionGO:0047369 succinate-hydroxymethylglutarate CoA-transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000007 Autosomal recessive inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in homozygotes. In the context of medical genetics, autosomal recessive disorders manifest in homozygotes (with two copies of the mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele)." [HPO:curators]
Show

 HP:0000822 Hypertension "High blood pressure." [HPO:curators]
Show

 HP:0000836 Hyperthyroidism "Hyperthyroidism refers to excessive secretion of thyroid hormone." [HPO:curators]
Show

 HP:0000853 Goiter "An enlargement of the thyroid gland." [HPO:curators]
Show

 HP:0001508 Failure to thrive 
Show

 HP:0002013 Vomiting 
Show

 HP:0002014 Diarrhea 
Show

 HP:0003150 Glutaric aciduria 
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr