ENSG00000175727


Homo sapiens

Features
Gene ID: ENSG00000175727
  
Biological name :MLXIP
  
Synonyms : MLX interacting protein / MLXIP / Q9HAP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.31
Gene start: 122078722
Gene end: 122147347
  
Corresponding Affymetrix probe sets: 1554886_a_at (Human Genome U133 Plus 2.0 Array)   202519_at (Human Genome U133 Plus 2.0 Array)   211789_s_at (Human Genome U133 Plus 2.0 Array)   225157_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445891
Ensembl peptide - ENSP00000440769
Ensembl peptide - ENSP00000444507
Ensembl peptide - ENSP00000312834
Ensembl peptide - ENSP00000366236
Ensembl peptide - ENSP00000438206
NCBI entrez gene - 22877     See in Manteia.
OMIM - 608090
RefSeq - XM_006719294
RefSeq - NM_014938
RefSeq - XM_006719290
RefSeq - XM_006719291
RefSeq - XM_006719292
RefSeq - XM_006719293
RefSeq Peptide - NP_055753
swissprot - F5H321
swissprot - H0YGR9
swissprot - F5H0V4
swissprot - Q9HAP2
Ensembl - ENSG00000175727
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mlxipENSDARG00000059474Danio rerio
 MLXIPENSGALG00000004397Gallus gallus
 MlxipENSMUSG00000038342Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MLXIPL / Q9NP71 / MLX interacting protein likeENSG0000000995036
MLX / Q9UH92 / MLX, MAX dimerization proteinENSG000001087888


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032648  MLX-interacting protein
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:1900402 regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0000989 transcription factor activity, transcription factor binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr