ENSG00000176340


Homo sapiens

Features
Gene ID: ENSG00000176340
  
Biological name :COX8A
  
Synonyms : COX8A / cytochrome c oxidase subunit 8A / P10176
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.1
Gene start: 63974607
Gene end: 63976543
  
Corresponding Affymetrix probe sets: 201119_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321260
NCBI entrez gene - 1351     See in Manteia.
OMIM - 123870
RefSeq - NM_004074
RefSeq Peptide - NP_004065
swissprot - P10176
swissprot - Q53XN1
Ensembl - ENSG00000176340
  
Related genetic diseases (OMIM): 220110 - ?Mitochondrial complex IV deficiency, 220110
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cox8bENSDARG00000097209Danio rerio
 ENSGALG00000045362Gallus gallus
 Cox8aENSMUSG00000035885Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AP000721.1ENSG0000025610065


Protein motifs (from Interpro)
Interpro ID Name
 IPR003205  Cytochrome c oxidase, subunit 8
 IPR036548  Cytochrome c oxidase, subunit 8 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006091 generation of precursor metabolites and energy TAS
 biological_processGO:0006123 mitochondrial electron transport, cytochrome c to oxygen IBA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:1902600 proton transmembrane transport IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005751 mitochondrial respiratory chain complex IV IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004129 cytochrome-c oxidase activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
TP53 Regulates Metabolic Genes
Respiratory electron transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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