ENSG00000176485


Homo sapiens

Features
Gene ID: ENSG00000176485
  
Biological name :PLA2G16
  
Synonyms : P53816 / phospholipase A2 group XVI / PLA2G16
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.1
Gene start: 63573195
Gene end: 63616883
  
Corresponding Affymetrix probe sets: 209581_at (Human Genome U133 Plus 2.0 Array)   235110_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000320337
Ensembl peptide - ENSP00000492682
Ensembl peptide - ENSP00000442576
Ensembl peptide - ENSP00000389124
NCBI entrez gene - 11145     See in Manteia.
OMIM - 613867
RefSeq - XM_006718426
RefSeq - NM_001128203
RefSeq - NM_007069
RefSeq Peptide - NP_001121675
RefSeq Peptide - NP_009000
swissprot - P53816
swissprot - A0A1W2PRW4
swissprot - A0A024R561
swissprot - F5H7E5
Ensembl - ENSG00000176485
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8R3U1ENSMUSG00000060675Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NWW9 / HRASLS2 / HRAS like suppressor 2ENSG0000013332868
Q9UL19 / RARRES3 / retinoic acid receptor responder 3ENSG0000013332148
Q96KN8 / HRASLS5 / HRAS like suppressor family member 5ENSG0000016800446
HRASLS / HRAS like suppressorENSG0000012725244


Protein motifs (from Interpro)
Interpro ID Name
 IPR007053  LRAT-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006641 triglyceride metabolic process ISS
 biological_processGO:0006644 phospholipid metabolic process IDA
 biological_processGO:0007031 peroxisome organization ISS
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0016042 lipid catabolic process ISS
 biological_processGO:0036149 phosphatidylinositol acyl-chain remodeling TAS
 biological_processGO:0036150 phosphatidylserine acyl-chain remodeling TAS
 biological_processGO:0036151 phosphatidylcholine acyl-chain remodeling TAS
 biological_processGO:0036152 phosphatidylethanolamine acyl-chain remodeling TAS
 biological_processGO:0045786 negative regulation of cell cycle IEA
 biological_processGO:0046485 ether lipid metabolic process ISS
 biological_processGO:1904177 regulation of adipose tissue development ISS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005777 peroxisome ISS
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004623 phospholipase A2 activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008970 phosphatidylcholine 1-acylhydrolase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052739 phosphatidylserine 1-acylhydrolase activity IEA
 molecular_functionGO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity IEA
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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