ENSG00000176946


Homo sapiens

Features
Gene ID: ENSG00000176946
  
Biological name :THAP4
  
Synonyms : Q8WY91 / THAP4 / THAP domain containing 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q37.3
Gene start: 241584405
Gene end: 241637449
  
Corresponding Affymetrix probe sets: 220417_s_at (Human Genome U133 Plus 2.0 Array)   224057_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482312
Ensembl peptide - ENSP00000384352
Ensembl peptide - ENSP00000385006
Ensembl peptide - ENSP00000385931
NCBI entrez gene - 51078     See in Manteia.
OMIM - 612533
RefSeq - XM_017004256
RefSeq - NM_001164356
RefSeq - NM_015963
RefSeq - XM_005247016
RefSeq - XM_011511291
RefSeq Peptide - NP_001157828
RefSeq Peptide - NP_057047
swissprot - Q8WY91
swissprot - Q9BQ29
swissprot - B5MCC0
Ensembl - ENSG00000176946
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thap4ENSDARG00000077323Danio rerio
 THAP4ENSGALG00000006283Gallus gallus
 Thap4ENSMUSG00000026279Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
THAP5 / Q7Z6K1 / THAP domain containing 5ENSG0000017768316
THAP8 / Q8NA92 / THAP domain containing 8ENSG0000016127711
THAP1 / Q9NVV9 / THAP domain containing 1ENSG0000013193111
THAP2 / Q9H0W7 / THAP domain containing 2ENSG0000017345110
THAP3 / Q8WTV1 / THAP domain containing 3ENSG0000004198810
AC073612.1ENSG000002580645


Protein motifs (from Interpro)
Interpro ID Name
 IPR006612  THAP-type zinc finger
 IPR012674  Calycin
 IPR014878  Domain of unknown function DUF1794


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0020037 heme binding IMP
 molecular_functionGO:0042803 protein homodimerization activity IMP
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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