ENSG00000177684


Homo sapiens

Features
Gene ID: ENSG00000177684
  
Biological name :DEFB114
  
Synonyms : DEFB114 / defensin beta 114 / Q30KQ6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p12.3
Gene start: 49960249
Gene end: 49964105
  
Corresponding Affymetrix probe sets: 1567878_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312702
NCBI entrez gene - 245928     See in Manteia.
OMIM - 615243
RefSeq - NM_001037499
RefSeq Peptide - NP_001032588
swissprot - Q30KQ6
Ensembl - ENSG00000177684
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR025933  Beta-defensin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006952 defense response IEA
 biological_processGO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway IDA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IMP
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0050729 positive regulation of inflammatory response IMP
 biological_processGO:0050829 defense response to Gram-negative bacterium IMP
 biological_processGO:0050830 defense response to Gram-positive bacterium IMP
 biological_processGO:0061760 antifungal innate immune response IMP
 biological_processGO:1904468 negative regulation of tumor necrosis factor secretion IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0001530 lipopolysaccharide binding IDA


Pathways (from Reactome)
Pathway description
Beta defensins
Defensins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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