ENSG00000178718


Homo sapiens

Features
Gene ID: ENSG00000178718
  
Biological name :RPP25
  
Synonyms : Q9BUL9 / ribonuclease P and MRP subunit p25 / RPP25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q24.2
Gene start: 74954416
Gene end: 74957464
  
Corresponding Affymetrix probe sets: 219143_s_at (Human Genome U133 Plus 2.0 Array)   223415_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317691
NCBI entrez gene - 54913     See in Manteia.
RefSeq - NM_017793
RefSeq Peptide - NP_060263
swissprot - Q9BUL9
Ensembl - ENSG00000178718
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpp25aENSDARG00000101536Danio rerio
 rpp25bENSDARG00000112256Danio rerio
 RPP25ENSGALG00000023859Gallus gallus
 Rpp25ENSMUSG00000062309Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N5L8 / RPP25L / ribonuclease P/MRP subunit p25 likeENSG0000016496736


Protein motifs (from Interpro)
Interpro ID Name
 IPR002775  DNA/RNA-binding protein Alba-like
 IPR036882  Alba-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001682 tRNA 5"-leader removal TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 cellular_componentGO:0000172 ribonuclease MRP complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0030681 multimeric ribonuclease P complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004526 ribonuclease P activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
tRNA processing in the nucleus
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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